Non-Cancerous Chronic Pain as a Risk Factor of Opioid Use Disorder (OUD): A Systematic Review

Abstract

Non-Cancerous Chronic Pain (NCCP) is a prevalent condition that imposes significant health costs on individuals and the healthcare system. This article presents a systematic review of the relationship between NCCP and the risk of developing Opioid Use Disorder (OUD). A comprehensive search was conducted using multiple databases to identify relevant studies published between 2005 and 2023. Findings suggest a strong connection between NCCP and the development of OUD, with individuals who use opioids for pain management being at risk of opioid misuse and addiction. Contributing factors include prolonged opioid use, increased dosages, comorbid psychiatric disorders, and the underlying pain condition. The review recommends a comprehensive approach to managing NCCP that incorporates non-opioid interventions, responsible prescribing practices, patient education, and multimodal treatment strategies. Further research and policy interventions are necessary to improve addiction treatment resources and expand access to non-pharmacological approaches for managing chronic pain.